Homology Modeling of Dopamine Receptors and Docking Study
Gupta, Manish K. / Singh, Gagandip / Kumar, Ankit
Dopamine receptors (DRs) belong to the class A of G-protein coupled receptors (GPCRs) super family. The five subtypes of dopamine receptors (DRs) i.e. D1R, D2R, D3R, D4R and D5R have been characterized and classified in D1-like (D1R and D5R, stimulatory) and D2-like (D2R, D3R, and D4R, inhibitory) subfamilies based on their sequence similarities and physiological response. The DRs are involved in many physiological processes and thus, deregula...